AKA
- Cemetifying Fibroma, Cemento-Ossifying Fibroma
Incidence
- rare; 3rd and 4th decade but can occur across a wide age range, female > male
Clinical Presentation
- a true neoplasm (osteogenic neoplasm) with a significant growth potential. Composed of fibrous tissue that contains variable mixture of bony trabeculae and/or cementum-like spherules. Painless swelling causing obvious facial asymmetry. Rarely cause pain or paresthesia.
Location
- mandible > maxilla; mandibular premolar and molar areas
Radiographic Features
- well defined and unilocular; may have sclerotic border; can be radiolucent but depending on amount of calcified material may appear with varying degrees of radiopacity; root divergence and resorption often associated with lesion
Compare to
- Focal Cemento-Osseous Dysplasia
Histopathology
- may show fibrous capsule surrounding tumor; bone trabeculae vary in size and frequently demonstrate a mixture of women and lamellar patterns. Variations in the types of mineralized material help distinguish from fibrous dysplasia (more uniform pattern of osseous differentiation)
Treatment
- circumscribed nature generally permits enucleation; larger lesions may require surgical excision
Hyperparathyroidism-jaw tumor syndrome – characterized by parathyroid adenoma or carcinoma, ossifying fibromas of the jaw, renal cysts, and Wilms’ tumors
