Cause

  • Area of hematopoietic marrow that produces area of radiolucency. Can be a result of aberrant bone regeneration after tooth extraction, persistent fetal marrow, marrow hyperplasia in response to increased demand for erythrocytes.

Incidence

  • 75% are adult women

Location

  • 70% occur in posterior mandible, most often in edentulous areas

Clinical Features

  • Typically asymptomatic and found incidentally on a radiographic exam

Radiographic Features

  • Often well circumscribed.
  • On highly detailed periapical radiographs, defect exhibit ill-defined borders and fine central trabeculations.
  • No expansion of bone is noted.

Histopathology

  • Cellular hematopoietic and fatty marrow.

Treatment

  • Once diagnosis is established, no treatment is needed.
Focal Osteoporotic Marrow Defect