Cause

  • Locally destructive inflammatory condition of the salivary glands
  • Result of ischemia of the salivary tissue that leads to local infarction
  • Predisposing factors that may compromise blood supply to the involved gland include: traumatic injuries, dental infections, ill-fitting dentures, upper respiratory infections, adjacent tumors, previous surgery

Incidence

  • More common in adults, mean age 46
  • Male > female

Location

  • 75% occur in posterior palate (hard palate > soft palate)

Clinical Presentation

  • Initially nonulcerated swelling often associated with pain and paresthesia
  • Within 2 weeks, necrotic tissue sloughs, leaving a craterlike ulcer

Compare to

  • Mimics malignant disease; subacute necrotizing sialadenitis

Treatment

  • Biopsy to confirm diagnosis
  • Heals spontaneously within 5 to 6 weeks
Necrotizing Sialometaplasia
Necrotizing Sialometaplasia