Fibro-Osseous Lesions

Osteogenesis Imperfecta Osteopetrosis Cleidocranial Dysplasia Focal Osteoporotic Marrow Defect Idiopathic Osteosclerosis Massive Osteolysis Paget’s Disease of Bone Central Giant Cell Granuloma Cherubism Simple Bone Cyst Aneurysmal Bone Cyst Fibrous Dysplasia Cemento-Osseous Dysplasias Familial Gigantiform Cementoma Ossifying Fibroma Juvenile Ossifying Fibroma Osteoma Gardner Syndrome Osteoblastoma and Osteoid Osteoma Cementoblastoma Chondroma Chondromyxoid Fibroma Synovial Chondromatosis Desmoplastic Fibroma Osteosarcoma […]

AKA Cemetifying Fibroma, Cemento-Ossifying Fibroma Incidence rare; 3rd and 4th decade but can occur across a wide age range, female > male Clinical Presentation a true neoplasm (osteogenic neoplasm) with a significant growth potential. Composed of fibrous tissue that contains variable mixture of bony trabeculae and/or cementum-like spherules. Painless swelling causing obvious facial asymmetry. Rarely

Focal vs Periapical vs Florid Most common fibro-osseous lesion Arise in close approximation with PDL ang have histopathologic similarities with the structure Histopathology: fragments of cellular mesenchymal tissue composed of spindle-shaped fibroblasts and collagen fibers with numerous small blood vessels Treatment: regular recall exam; unless symptomatic due to chronic osteomyelitis involving dysplastic bone and cementum,

Fibrous dysplasia is a developmental tumorlike condition that is characterized by replacement of normal bone by an excessive proliferation of cellular fibrous connective tissue intermixed with irregular bony trabeculae. Cause Sporadic condition that results from a postzygotic mutation in the GNAS1 (guanine nucleotide-binding protein, α-stimulating activity polypeptide 1) gene. Constitutive activation of G protein signaling