Serotonin Syndrome

Serotonin Syndrome

Pharmacology

Serotonin syndrome is characterized by confusion, agitation, tachycardia, fever, hyperreflexia, and myoclonus. Normeperidine is an active metabolite of meperidine metabolism and has a half-life of 15 to 30 hours in an adult. Normeperidine’s elimination is dependent upon renal function and can accumulate with high repeated dosages or in the presence of renal impairment. Serotonin antagonists,

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Methohexital

Pharmacology

Administration of methohexital produces modest decreases in systemic blood pressure that are transient due to compensatory increase in heart rate. This decrease in systemic blood pressure is principally due to peripheral vasodilatation. The resulting dilation of peripheral capacitance vessels leads to pooling of blood, decreased venous return and the potential for decreases in cardiac output

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Etomidate

Etomidate

Pharmacology

Etomidate is one of the few anesthetics that suppresses the adrenocortical axis. Etomidate causes adrenocortical suppression by producing a dose-dependent inhibition of the enzyme 11-beta-hydroxylase which is necessary for conversion of cholesterol to cortisol. This suppression lasts 4 to 8 hours after an induction dose of etomidate. Etomidate maintains hemodynamic stability and has little effect

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Freys Syndrome

Frey’s Syndrome

Medicine

Frey syndrome, or “gustatory sweating” is a relatively common complication of parotidectomy but uncommon following temporomandibular joint arthrotomy. It is believed to be caused by aberrant regeneration of postganglionic parasympathetic parotid secretomotor fibers with severed post-ganglionic sympathetic fibers innervating facial sweat glands.

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Horners Syndrome

Horner’s Syndrome

Medicine

Caused by a disruption in the sympathetic innervation to the ipsilateral maxillofacial region, is characterized by: Ptosis (by loss of sympathetic innervation to Mueller’s muscle) Anhidrosis (by interruption of sympathetic innervation to cutaneous sweat glands). Miosis or a constricted pupil (by unopposed parasympathetic constriction) Remember the pnemonic, PAM is Horny (Ptosis, Anhydrosis, Miosis is Horner’s

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Superior Orbital Fissure Syndrome Vs Orbital Apex Syndrome

Superior Orbital Fissure Syndrome VS Orbital Apex Syndrome

Oral & Maxillofacial Surgery

Symptoms of superior orbital fissure syndrome include: Pupillary dilation via alteration in cranial nerve III function in it’s innervation of the pupillary constrictors. Paresis of cranial nerves III, IV, and IV causing ophthalmoplegia. Cranial nerve III involvement causes paresis of the levator palpebrae superiorus muscle, leading to ptosis and loss of the superior palpebral fold.

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Monitors

Monitors

Anesthesia

Blood Pressure Cuff When considering the correct size of cuff, two pertinent points should be recalled: The inflatable bladder in the cuff should be able to completely encircle the arm with minimal overlap. The width of the bladder in the cuff should be approximately 20% greater than the diameter of the extremity used for the

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Glasgow Coma Score Gcs

Glasgow Coma Score (GCS)

Medicine

Glasgow Coma Scale (GCS): Interpretation, Posturing, and Airway Management The Glasgow Coma Scale (GCS) is one of the most widely used clinical tools for assessing level of consciousness in patients with head injury, neurologic trauma, or altered mental status. It provides a standardized method for evaluating neurologic function and plays a critical role in trauma

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